1. The reduced risk of punctures. No longer is there a chance of pinch-flats, caused when you over-compress and pinch the inner tube. You also significantly reduce the chance of thorns or flints causing a leak; as the sealant should seal around any intruding objects.

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2.The benefits of tubeless road extend far beyond puncture protection though, into the realms of grip and comfort.  A good tubeless set-up can be a lot more comfortable, and have better grip than a tubed combination. This is because the tyre is allowed to conform to the road surface to a greater extent; so rather than bouncing over it, you remain firmly planted.

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3. Reduced friction on tubeless systems. Unbeknown to many, there is actually more friction when a tyre is bouncing over a surface; so by reducing this, you reduce the friction between bike and road. Tubeless tyres also have less friction because the inner tube is not moving around inside the tyre; preventing it from changing shape optimally, as the tyre rolls along